Living a minimalist life has always been important to me, and while I do collect a fair bit of stuff, I'm not attached to a lot of it except for a few sentimental pieces and my books (as a few people have mentioned here).
In the run-up to going to Nepal in November, I've been getting rid of my stuff. I'm trying to get rid of most of my superfluous clothes, and all furniture must go (I only have a few bookshelves and one beautiful desk). I've gotten a pile of boxes, and I've been trying to find time to categorize all of my books so I can effectively store them in my father's house, but still have access to them if I email him "Dad, I need you to mail me The End of History and the Last Man as soon as you can. It's in box number 4."
But really, books are all I'm attached to. Music and Movies I rip to my computer, so I can do without the physical DvDs or CDs. I've thought about eReaders, and doing a similar thing with my book collection, but even though I'd like to have a digital copy of all my books, I would want to have the physical books also. There's something tactile and reassuring about having worn pages under your fingers, and displaying them on the shelf. And if the power goes out (or batteries die) I can still read my physical books, and that's a big difference between books and other media. If I had no access to electricity, my DVDs would be as useless as the movies on my hard drive. But my books are still usable even when dead batteries prevent me from reading my eBooks.
As far as transhumanism goes, I remember watching a TED talk on that submect. The point this guy makes is that Transhumanism is a false idea. Humans have always used creativity and invention to augment our natural abilities. We invented the spear to kill things. We took advantage of fire to expand the roster of things we could eat, as well as to compensate for lack of low-light vision. We wore the skins of wolves and bears to augment our ability to withstand the cold, and we tamed horses to cover larger distances. We invented the written word to aid with memory, and to proliferate ideas farther and longer (through time) than our own voices could carry. It's a continuing tradition, and we've become more and more 'transhuman' every step of the way ... and yet we are still human. To aspire to transhumanism, even while we fear transhumanism, is what it is to be human.