I enjoy Trigun, but it's one of those series that I can understand people not liking.... not like Bebop, I've physically pounced on people who talked crap about Bebop.
I don't like to be known as an 'anime/manga' fan. I have plenty of friends who are pretty gung-ho about it, and I see how people look at/deal with them, so I don't go nuts and hope that people don't dismiss me for a loony. All that said, though I have never actually hidden my affinity for anime or manga, the only anime/manga I have ever publicly and vehemently defended and downright proselytized about was
Cowboy Bebop. I think that's part of the reason I find it so difficult to take when people don't appreciate it like I do. It's one of the better shows (including western television) I've watched, and I want to share it, but it's difficult because people sometimes dismiss it as so much cartoon garbage.
I also really enjoyed
Full Metal Panic!, which hasn't been mentioned up to this point. It jumped back and forth between dark sci-fi and lighthearted romantic comedy a whole lot, but that was part of it's strength. Also an excellent dub.
My guilty anime pleasure is the
Gundam franchise. Nothing that's come out in the last ten years has been groundbreaking, or even incredibly entertaining, but the two series that stand out for me enough to talk about it and recommend it to people are
Mobile Suit Gundam: 08th MS Team, and
Mobile Suit Gundam: 0080, War in the Pocket.